willy wonka book week costume This review focuses on the deamidation of asparagine in monoclonal antibodies, one of the well-known degradation pathways.The importance of close monitoring of deamidation from early developability assessment to in vivo studies is discussed consequentially.The application of chromatographic and electrophoretic instrume
Hyperspectral remote sensing reveals detailed information about the optical response of a scene.Self-Organizing Maps (SOMs) can partition a hyperspectral dataset into clusters, both to enable more analysis on-board the imaging platform and to reduce downlink time.Here, the expected on-board performance of the SOM algorithm is calculated within two
During embryogenesis motor axons navigate to their target muscles, where individual motor axons develop complex branch morphologies.The mechanisms that control axonal branching morphogenesis have been studied intensively, yet it still remains unclear when branches begin to form or how branch locations are determined.Live cell imaging of individual
Background Measures of whole-body angular momentum in the sagittal plane are commonly used to characterize dynamic balance during human walking.To compute angular momentum, one must specify a reference point about which momentum is calculated.Although biomechanists primarily compute angular momentum about the center of mass (CoM), momentum-based co
The paper features the history of shaping the state border between the USA and Mexico in the XIX century in the context of the US foreign policy as well as the history of colonization of the territories which now make up the borderland region of present-day Mexico and the USA.The main trend of American foreign policy in the XIX century was continen